Standards and Ontologies for Functional Genomics: Towards Unified Ontologies for Biology and Biomedicine

Standards and Ontologies for Functional Genomics: Towards Unified Ontologies for Biology and Biomedicine

In recent years, whole genome analysis has become routine and systems biology and modelling of whole cells are becoming more common. Advances in experimental technology now permit expression analysis for tens of thousands of genes at a time, generating vast amounts of biological data, and the application of high-throughput technologies to proteomics makes the burden even heavier. Databases and ...

Standards and Ontologies for Functional Genomics 2

Like the first conference, held in 2002, on Standards and Ontologies for Functional Genomics (www.sofg.org), the second SOFG meeting brought together computer scientists, ontologists and biomedical scientists in Philadelphia to examine the state of the art in ontology technology, development and emerging standards for biomedicine. Briefly, an ontology is a means of formalizing knowledge about a...

Announcement: Standards and Ontologies for Functional Genomics (SOFG) Conference

The goal of this conference is to bring together scientists who are developing standards and ontologies for describing microarray and other high throughput functional genomics experiments. The topics will include: • The Gene Ontology (GO) project • Anatomy and phenotype ontologies • Disease ontologies • Chemical compounds and treatments • Inter-ontology mapping • Tools for ontology development ...

Towards Desiderata for Provenance Ontologies in Biomedicine

7 Ontologies and functional genomics

High-throughput methodologies have increased by orders of magnitude the possibility of obtaining data in orders of magnitude. Nevertheless, translating data into useful biological knowledge is not an easy task. We review how bioontologies, and in particular, gene ontology, can be used to understand the biological roles played by genes that account for the phenotypes studied, which is the ultima...